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Safety evaluation of microbial pesticide (HaNPV) based on PCR method
Miao Zhao, Shufei Li, Qinghong Zhou, Dianming Zhou, Ning He, Zhiyong Qian
《化学科学与工程前沿(英文)》 2019年 第13卷 第2期 页码 377-384 doi: 10.1007/s11705-018-1777-9
关键词: microbial pesticides HaNPV acute intravenous injection infectivity pathogenicity
《医学前沿(英文)》 doi: 10.1007/s11684-023-1001-2
关键词: iron deficiency anemia intravenous iron ferric carboxymaltose iron sucrose Hb response early response
A novel intravenous general anesthetic--- emulsified isoflurane: from bench to bedside
null
《医学前沿(英文)》 2012年 第6卷 第4期 页码 381-387 doi: 10.1007/s11684-012-0229-z
Application of volatile anesthetics greatly alters modern medicine. There are obvious advantages of volatile anesthetics such as strong anesthetic potency, rapid onset and elimination through respiration system. Isoflurane is one of the most widely used volatile anesthetics in clinic. Emulsified isoflurane, the emulsion of isoflurane, is a novel intravenous general anesthetic. With the development of emulsified isoflurane in the past fifteen years, its utility has spread from intravenous general anesthesia to various fields including regional anesthesia, organ protection, as well as anesthetic pharmacological study. In this review, we will summarize literatures of emulsified isoflurane about its history, clinical application and future potential utility in the above mentioned fields.
关键词: emulsified isoflurane (EI) general anesthesia regional anesthesia organ protection anesthetic pharmacological study
Three-dimensional numerical simulation for plastic injection-compression molding
Yun ZHANG, Wenjie YU, Junjie LIANG, Jianlin LANG, Dequn LI
《机械工程前沿(英文)》 2018年 第13卷 第1期 页码 74-84 doi: 10.1007/s11465-018-0490-1
Compared with conventional injection molding, injection-compression molding can mold optical parts with higher precision and lower flow residual stress. However, the melt flow process in a closed cavity becomes more complex because of the moving cavity boundary during compression and the nonlinear problems caused by non-Newtonian polymer melt. In this study, a 3D simulation method was developed for injection-compression molding. In this method, arbitrary Lagrangian-Eulerian was introduced to model the moving-boundary flow problem in the compression stage. The non-Newtonian characteristics and compressibility of the polymer melt were considered. The melt flow and pressure distribution in the cavity were investigated by using the proposed simulation method and compared with those of injection molding. Results reveal that the fountain flow effect becomes significant when the cavity thickness increases during compression. The back flow also plays an important role in the flow pattern and redistribution of cavity pressure. The discrepancy in pressures at different points along the flow path is complicated rather than monotonically decreased in injection molding.
关键词: injection-compression molding simulation injection molding melt flow cavity pressure
Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu
《医学前沿(英文)》 2021年 第15卷 第1期 页码 108-115 doi: 10.1007/s11684-019-0730-8
关键词: post-transplantation cyclophosphamide allogeneic hematopoietic stem cell transplantation lymphoid malignancies
density measurement for plastic injection molding via ultrasonic technology
《机械工程前沿(英文)》 2022年 第17卷 第4期 doi: 10.1007/s11465-022-0714-2
关键词: ultrasonic measurement melt density in-situ measurement injection molding
Trend prediction technology of condition maintenance for large water injection units
Xiaoli XU, Sanpeng DENG
《机械工程前沿(英文)》 2010年 第5卷 第2期 页码 171-175 doi: 10.1007/s11465-009-0091-0
关键词: water injection units condition-based maintenance trend prediction
Intelligent methods for the process parameter determination of plastic injection molding
Huang GAO, Yun ZHANG, Xundao ZHOU, Dequn LI
《机械工程前沿(英文)》 2018年 第13卷 第1期 页码 85-95 doi: 10.1007/s11465-018-0491-0
Injection molding is one of the most widely used material processing methods in producing plastic products with complex geometries and high precision. The determination of process parameters is important in obtaining qualified products and maintaining product quality. This article reviews the recent studies and developments of the intelligent methods applied in the process parameter determination of injection molding. These intelligent methods are classified into three categories: Case-based reasoning methods, expert system-based methods, and data fitting and optimization methods. A framework of process parameter determination is proposed after comprehensive discussions. Finally, the conclusions and future research topics are discussed.
关键词: injection molding intelligent methods process parameters optimization
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
《医学前沿(英文)》 2010年 第4卷 第4期 页码 356-362 doi: 10.1007/s11684-010-0220-5
《能源前沿(英文)》 2023年 第17卷 第5期 页码 678-691 doi: 10.1007/s11708-022-0859-z
关键词: gasoline compression ignition injection strategy fuel stratification high efficiency high load
CO, N, and CO/N mixed gas injection for enhanced shale gas recovery and CO geological storage
《能源前沿(英文)》 2023年 第17卷 第3期 页码 428-445 doi: 10.1007/s11708-023-0865-9
关键词: shale gas gas injection competitive adsorption enhanced shale gas recovery CO2 geological storage
Precision medicine in acute lymphoblastic leukemia
Ching-Hon Pui
《医学前沿(英文)》 2020年 第14卷 第6期 页码 689-700 doi: 10.1007/s11684-020-0759-8
关键词: acute lymphoblastic leukemia molecular therapeutics targeted therapy tyrosine kinase inhibitors immunotherapy CAR T-cell therapy
Experimental study of stratified lean burn characteristics on a dual injection gasoline engine
Chun XIA, Tingyu ZHAO, Junhua FANG, Lei ZHU, Zhen HUANG
《能源前沿(英文)》 2022年 第16卷 第6期 页码 900-915 doi: 10.1007/s11708-021-0812-6
关键词: dual injection stratified lean burn gasoline engine particulate matter emission combustion analysis
Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia
null
《医学前沿(英文)》 2015年 第9卷 第1期 页码 1-9 doi: 10.1007/s11684-015-0381-3
With the cure rate of childhood acute lymphoblastic leukemia (ALL) approaching 90%, further improvement in the treatment outcome and quality of life of patients will require better understanding of the mechanisms of drug resistance, identifying new leukemic cell genetic lesions that are amendable to available target therapy, and optimizing treatment based on host pharmacodynamics and pharmacogenomics. Deeper characterization of leukemic cell genetic abnormalities has discovered new subtypes of leukemia such as early T-cell precursor ALL and Philadelphia chromosome-like ALL, and identified many genomic alterations that have diagnostic, prognostic, or therapeutic implications. In this regard, several novel fusion transcripts are responsive to ABL tyrosine kinase inhibitors and potentially to JAK inhibitors. Genome-wide analyses have also unraveled the role of inherited cancer predisposing genes and small nucleotide polymorphisms of several genes in the development of childhood ALL. These advances promise to lead to more sophisticated personalized treatment strategies in the near future.
关键词: pharmacogenomics acute lymphoblastic leukemia genomics pharmacogenetics
标题 作者 时间 类型 操作
Safety evaluation of microbial pesticide (HaNPV) based on PCR method
Miao Zhao, Shufei Li, Qinghong Zhou, Dianming Zhou, Ning He, Zhiyong Qian
期刊论文
A randomized, controlled, open label non-inferiority trial of intravenous ferric carboxymaltose versus
期刊论文
Three-dimensional numerical simulation for plastic injection-compression molding
Yun ZHANG, Wenjie YU, Junjie LIANG, Jianlin LANG, Dequn LI
期刊论文
Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneic
Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu
期刊论文
Trend prediction technology of condition maintenance for large water injection units
Xiaoli XU, Sanpeng DENG
期刊论文
Intelligent methods for the process parameter determination of plastic injection molding
Huang GAO, Yun ZHANG, Xundao ZHOU, Dequn LI
期刊论文
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
期刊论文
methodology for regulating fuel stratification and improving fuel economy of GCI mode via double main-injection
期刊论文
Experimental study of stratified lean burn characteristics on a dual injection gasoline engine
Chun XIA, Tingyu ZHAO, Junhua FANG, Lei ZHU, Zhen HUANG
期刊论文